The takeaway
Annexon Inc shows a pronounced seasonal pattern over 6 years of data — strongest in June (+14.0%) and softest in March (−14.6%).
Right now
In July, the stock has risen 50% of years, averaging +7.6%, about +5.4 pts better than the S&P 500.
The full picture
Annexon Inc's most dependable month has been June, higher in 5 of 5 years; March has been its least reliable, up just 20% of the time.
| Year | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Win rate % | ||||||||||||
| Median return % | ||||||||||||
| 2025 | ||||||||||||
| 2024 | ||||||||||||
| 2023 | ||||||||||||
| 2022 | ||||||||||||
| 2021 | ||||||||||||
| 2020 | — | — | — | — | — | — |
Month by month
The stock's clearest edge over the S&P 500 lands in June (+13.8 pts); it has trailed the market most in March (−15.6 pts).
“vs S&P” is Annexon Inc’s average for a month minus the S&P 500’s average for that same month — isolating Annexon Inc’s own seasonal edge from broad market drift.
Reality check
Over the last 5 years, June has closed higher 100% of the time versus 100% across the last 6 years — the pattern is holding.
Figures are the typical (median) June return and how often it rose — the last 5 years versus the last 6(the heatmap’s default window). This verdict stays anchored to that 6-year window even if you zoom the chart, so it never disagrees with the badges above.
In plain English
Strip the year back and a single month does the heavy lifting: June, up in all 5 Junes while the other eleven tend to blur together.
Its average (+14.0%) and median (+13.2%) land within a hair of each other — the tell of steady, year-after-year gains rather than one outlier doing the work. It is also the calendar's calmest month, its returns swinging least from year to year (a 7.5% spread), and even its worst June in 6 years lost only 6.0% — the gentlest downside anywhere on its calendar. Crucially, the gain is the stock's own rather than a rising tide's: June has cleared the S&P 500 by +13.8 points above the index. That consistency sets it apart from the field, where the average stock manages June only about 52% of the time.
A few other months pull their weight: May, September, and November have also closed higher more often than not. At the other end of the calendar, March has been the soft spot — the weakest of 7 months that average a loss (−14.6%), and the edge isn't year-round — the stock has trailed the S&P 500 in March, January, and October. Its roughest month on record was a −45.1% May in 2023 — a reminder of how hard even a seasonal name can fall.
June has now closed higher 5 years running.
The takeaway is less about when to buy than what to expect: June aside, the stock's months offer little reliable tilt. With a short 6-year record and returns that swing hard year to year, the signal is best held loosely.
Short answers on the stock's best month (June), its worst (March), and whether it really trades seasonally.
Yes, to a pronounced degree. Since 2020 its best month (June, +14.0%) has run well ahead of its worst (March, −14.6%) — the heatmap above shows how steady that gap has been year to year.
June has been the strongest, averaging +14.0% and closing higher in all 5 years on record since 2020.
It's the weakest, averaging −14.6% — historically a soft spot, though it still varies from year to year.
Explore
These names have the strongest July track records on record — a starting point for comparison.
Before you trade